Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449868 | 0.93 | SLC9A3 (0.81) | SLC9A3 | |
| SCHEMBL16638251 | 0.92 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL16638606 | 0.90 | SLC9A3 (0.65) | SLC9A3 | |
| SCHEMBL13449813 | 0.89 | SLC9A3 (0.73) | SLC9A3 | |
| SCHEMBL17988594 | 0.89 | SLC9A3 (0.89) | SLC9A3 | |
| SCHEMBL20953657 | 0.89 | SLC9A3 (0.89) | SLC9A3 | |
| SCHEMBL16638241 | 0.87 | SLC9A3 (0.65) | SLC9A3 | |
| SCHEMBL2571107 | 0.86 | SLC9A3 (0.79) | SLC9A3 | |
| SCHEMBL2571112 | 0.86 | SLC9A3 (0.79) | SLC9A3 | |
| SCHEMBL13449814 | 0.86 | SLC9A3 (0.69) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006281-B2 | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders | ARDELYX, INC. (US) | 2015-04-14 | — | — | US | disclosed |