SCHEMBL16638273

SCHEMBL16638273

CC(=O)[C@@H](N)CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ NOD1 Q9Y239 8/20 0.50
▸ FOLH1 Q04609 2/20 0.43
▸ FNTA P49354 1/20 0.43
▸ FNTB P49356 1/20 0.43
▸ CCKAR P32238 1/20 0.42
▸ CCKBR P32239 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16638274 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL16947959 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL15357538 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL24891117 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL16947828 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL24890886 1.00 GLP1R (0.67) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL21243001 0.99 GLP1R (0.66) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL14438782 0.94 GLP1R (0.74) GLP1RNOD1
SCHEMBL24249859 0.93 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL24249840 0.93 GLP1R (0.68) GLP1RNOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165313-A1 EGF(A) ANALOGUES, PREPARATION, FORMULATIONS AND USES THEREOF NOVO NORDISK A/S (DK) 2020-05-28 — — US disclosed
US-9006178-B2 Double-acylated GLP-1 derivatives with a linker NOVO NORDISK A/S (DK) 2015-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165313-A1 EGF(A) ANALOGUES, PREPARATION, FORMULATIONS AND USES THEREOF EGFR, VEGFA, ERBB2 GLP1R 30/4885NOD1 4450/4885FOLH1 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback