Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623011 | 0.90 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL623141 | 0.89 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL621419 | 0.84 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL622459 | 0.82 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL14992463 | 0.80 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL621998 | 0.78 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL623414 | 0.78 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL623649 | 0.78 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL622190 | 0.77 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL621094 | 0.77 | EGLN1 (1.00) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006251-B2 | 4-aminoquinazolin-2-yl-1-pyrrazole-4-carboxylic acid compounds as prolyl hydroxylase inhibitors | JANSSEN PHARAMCEUTICA NV (BE) | 2015-04-14 | — | — | US | disclosed |