Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805136 | 0.78 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL1274068 | 0.75 | — | — | |
| SCHEMBL10794688 | 0.75 | TSHR (0.46) | TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL22401684 | 0.72 | — | — | |
| SCHEMBL599877 | 0.69 | TSHR (0.50) | TSHRTDP1 | |
| SCHEMBL16812837 | 0.69 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL12179759 | 0.67 | — | — | |
| SCHEMBL18697049 | 0.67 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL13458323 | 0.67 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL17793493 | 0.67 | TSHR (0.32) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006281-B2 | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders | ARDELYX, INC. (US) | 2015-04-14 | — | — | US | disclosed |