Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18912870 | 0.89 | PAOX (0.51) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL16638640 | 0.89 | MEN1 (0.44) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL12791566 | 0.87 | KMT2A (0.52) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL14128878 | 0.85 | KMT2A (0.54) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL16638634 | 0.84 | MEN1 (0.43) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL7862774 | 0.83 | KMT2A (0.48) | MEN1KMT2ATSHRKDM5AMGAM | |
| SCHEMBL12847506 | 0.83 | KMT2A (0.48) | MEN1KMT2ATSHRKDM5AMGAM | |
| SCHEMBL12847693 | 0.83 | KMT2A (0.52) | MEN1KMT2APAOXTSHRKDM5A | |
| SCHEMBL12847507 | 0.82 | KMT2A (0.47) | MEN1KMT2ATSHRKDM5AMGAM | |
| SCHEMBL18912868 | 0.82 | KMT2A (0.47) | MEN1KMT2APAOXTSHRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |