Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903844 | 0.98 | KMT2A (0.47) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL15781720 | 0.94 | MEN1 (0.53) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL8203049 | 0.93 | KMT2A (0.52) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL12791549 | 0.93 | KMT2A (0.52) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL24727471 | 0.91 | KMT2A (0.54) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL12791486 | 0.91 | KMT2A (0.54) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL15781767 | 0.90 | KDM5A (0.43) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL15781691 | 0.89 | KMT2A (0.46) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL15781750 | 0.89 | KMT2A (0.46) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL15783047 | 0.89 | KMT2A (0.46) | KMT2AMEN1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |