Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638634 | 0.97 | MEN1 (0.43) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12847852 | 0.93 | KMT2A (0.48) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL16638640 | 0.92 | MEN1 (0.44) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12847507 | 0.91 | KMT2A (0.47) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12791479 | 0.91 | KMT2A (0.50) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12847692 | 0.91 | KMT2A (0.50) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12847506 | 0.90 | KMT2A (0.48) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL7862774 | 0.90 | KMT2A (0.48) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL12847693 | 0.89 | KMT2A (0.52) | MEN1KMT2ACA12CA14TSHR | |
| SCHEMBL15781714 | 0.88 | MEN1 (0.50) | MEN1KMT2ACA12CA14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |