Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116752 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610464 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL16628838 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116748 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610465 | 0.85 | HCRTR1 (0.48) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116937 | 0.85 | HCRTR1 (0.48) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL15177872 | 0.82 | HCRTR1 (0.39) | HCRTR1HCRTR2KCNH2OPRL1 | |
| SCHEMBL15177871 | 0.82 | HCRTR1 (0.45) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610688 | 0.75 | HCRTR1 (0.52) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118936 | 0.74 | HCRTR1 (0.73) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |