Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.80 |
| ▸ | HCRTR1 | O43613 | 19/20 | 0.80 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118622 | 0.89 | HCRTR2 (1.00) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL2116987 | 0.84 | HCRTR2 (1.00) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL2117063 | 0.80 | HCRTR2 (0.86) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL10189003 | 0.79 | HCRTR2 (1.00) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL10189011 | 0.78 | HCRTR2 (1.00) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL2610633 | 0.76 | HCRTR2 (0.84) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 | |
| SCHEMBL2119190 | 0.76 | HCRTR1 (0.85) | HCRTR2HCRTR1KCNH2 | |
| SCHEMBL2122401 | 0.76 | HCRTR1 (0.84) | HCRTR2HCRTR1KCNH2 | |
| SCHEMBL12150161 | 0.76 | HCRTR2 (0.83) | HCRTR2HCRTR1KCNH2 | |
| SCHEMBL2610621 | 0.76 | HCRTR2 (0.83) | HCRTR2HCRTR1CYP2C8CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |