Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.85 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117684 | 1.00 | HCRTR1 (0.85) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116453 | 0.93 | HCRTR1 (0.88) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2119209 | 0.93 | HCRTR1 (0.85) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118803 | 0.93 | HCRTR1 (0.75) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118808 | 0.93 | HCRTR1 (0.84) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL16628814 | 0.93 | HCRTR1 (0.84) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2122401 | 0.92 | HCRTR1 (0.84) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118472 | 0.92 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118521 | 0.92 | HCRTR1 (0.72) | HCRTR1HCRTR2KCNH2 | |
| Lemborexant SCHEMBL21084776 | 0.92 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |