Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118887 | 0.89 | HCRTR1 (0.57) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610414 | 0.82 | HCRTR1 (0.59) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116979 | 0.81 | HCRTR1 (0.62) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL22666392 | 0.81 | HCRTR1 (0.62) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL24533938 | 0.81 | HCRTR1 (0.62) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2120155 | 0.79 | HCRTR1 (0.55) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610708 | 0.79 | HCRTR1 (0.53) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116858 | 0.78 | HCRTR1 (0.49) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610419 | 0.78 | HCRTR1 (0.57) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL15161917 | 0.76 | HCRTR1 (0.61) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |