Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 18/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913434 | 0.87 | PDPK1 (0.66) | PDPK1 | |
| SCHEMBL1913422 | 0.77 | PDPK1 (0.50) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL12530673 | 0.77 | PDPK1 (0.50) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913409 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913517 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913410 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913597 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913534 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913630 | 0.75 | PDPK1 (0.64) | PDPK1 | |
| SCHEMBL1913530 | 0.75 | PDPK1 (0.73) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516431-B1 | PYRROLOPYRIDINYL-PYRIMIDIN-2-YLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | disclosed |