Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913502 | 0.94 | PDPK1 (0.77) | PDPK1 | |
| SCHEMBL1913509 | 0.94 | PDPK1 (0.77) | PDPK1 | |
| SCHEMBL1913503 | 0.94 | PDPK1 (0.77) | PDPK1 | |
| SCHEMBL15227713 | 0.88 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL1913616 | 0.86 | PDPK1 (0.80) | PDPK1 | |
| SCHEMBL1913507 | 0.86 | PDPK1 (0.80) | PDPK1 | |
| SCHEMBL1913394 | 0.86 | PDPK1 (0.80) | PDPK1 | |
| SCHEMBL1913530 | 0.85 | PDPK1 (0.73) | PDPK1 | |
| SCHEMBL1913455 | 0.84 | PDPK1 (0.74) | PDPK1 | |
| SCHEMBL1913401 | 0.84 | PDPK1 (0.71) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516431-B1 | PYRROLOPYRIDINYL-PYRIMIDIN-2-YLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | disclosed |