SCHEMBL166391

SCHEMBL166391

O=C(O)CC(C(=O)OCCOC(=O)C(CC(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3474302 0.96
SCHEMBL8741717 0.91
SCHEMBL2153353 0.85
SCHEMBL9008981 0.83
SCHEMBL8744936 0.83
SCHEMBL859389 0.83
SCHEMBL610721 0.79
Di(Hydroxyethyl)Ether SCHEMBL3474303 0.79
Ethylene Glycol SCHEMBL4563857 0.79
Ethylene Glycol SCHEMBL243462 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344635-B2 COVID-19 vaccine THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2025-07-01 US claimed
EP-4103585-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF Twinpig Biolab, Inc. (KR) 2022-12-21 EP claimed
WO-2022234346-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 WO claimed
US-20220354957-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 US claimed
US-11484601-B2 Targeting M2-like tumor-associated macrophages by using melittin-based proapoptotic peptide TWINPIGBIOLAB INC. (KR) 2022-11-01 US claimed
US-20210300970-A1 COVID-19 VACCINE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-09-30 US claimed
US-20210244823-A1 TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PROAPOPTOTIC PEPTIDE TWINPIGBIOLAB INC. (KR) 2021-08-12 US claimed
EP-3789041-A1 TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PRO-APOPTOTIC PEPTIDE Twinpigbiolab Inc. (KR) 2021-03-10 EP claimed
US-10605810-B2 Pincers comprising antibody and aptamer conjugated via a linker which binds to the same target material and use thereof UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2020-03-31 US claimed
US-20180263927-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2018-09-20 US claimed
WO-2009131909-A2 RECOMBINANT DEAMIDATED GLIADIN ANTIGEN BIO-RAD LABORATORIES, INC. (US) 2009-10-29 WO claimed
US-7604804-B2 Two gp120 binding molecules that target the CD4 binding pocket on a trimeric HIV gp120 complex and gp120 binding molecules are separated by a spacer/linker of sufficient length to provide for binding of the gp120 binding molecules to the CD-4 binding sites on trimeric gp120 sites on virion surface UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) 2009-10-20 US claimed
WO-2009092383-A2 PRODUCTS AND METHODS TO PREVENT INFECTION MULTIMERICS APS (DK) 2009-07-30 WO claimed
US-20080125365-A1 ISOLATED COMPLEXES OF COVALENTLY CROSS-LINKED ENDOTOXIN AND MODIFIED MD-2 UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2008-05-29 US claimed
WO-2008036838-A2 ISOLATED COMPLEXES OF COVALENTLY CROSS-LINKED ENDOTOXIN AND MODIFIED MD-2 UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2008-03-27 WO claimed
US-20070099225-A1 Separation of chromosomes using an affinity-based magnetic bead separation in suspension UNIVERSITY OF KANSAS 2007-05-03 US claimed
US-20050176642-A1 Enhancing anti-HIV efficiency through multivalent inhibitors targeting oligomeric GP120 UNIVERSITY OF MARYLAND, BALTIMORE 2005-08-11 US claimed
EP-0701448-B1 AMPLIFICATION OF THE VITAMIN B 12 UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY LTD (AU) 2002-08-14 EP claimed
WO-2001046461-A2 MODIFIED NUCLEIC ACIDS AND THEIR USE BIOCHIP TECHNOLOGIES GMBH (DE) 2001-06-28 WO claimed
EP-1111069-A1 Modified nucleic acids and their use BioChip Technologies GmbH (DE) 2001-06-27 EP claimed