SCHEMBL16639669

SCHEMBL16639669

CC(C)[Si](OCc1ccc(N)cc1)(C(C)C)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.42
PARP1 P09874 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
GFER P55789 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAOB P27338 8/20 0.39
APP P05067 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
MAOA P21397 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP19A1 P11511 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932721 0.82 PARP1 (0.39) IDO1PARP1ALDH1A1TSHR
SCHEMBL15298776 0.82 AGXT (0.48) IDO1PARP1ALDH1A1MAOBRAB9A
SCHEMBL9889127 0.82 TAAR1 (0.45) IDO1PARP1ALDH1A1CYP3A4
SCHEMBL6753184 0.80 PARP1 (0.39) IDO1PARP1
SCHEMBL109956 0.80 CYP3A4 (0.47) IDO1CYP3A4APP
SCHEMBL18824993 0.80 PARP1 (0.41) IDO1PARP1TSHR
SCHEMBL481295 0.80 IDO1 (0.47) IDO1PARP1ALDH1A1MAOBAPP
SCHEMBL1315107 0.79 TSHR (0.46) IDO1PARP1TDP1ALDH1A1TSHR
SCHEMBL145704 0.78 MAOB (0.43) IDO1PARP1CYP3A4MAOBMAOA
SCHEMBL1491341 0.77 TSHR (0.44) IDO1TDP1GFERALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589395-B Carbazole methylphenyl ether derivative, preparation method and application thereof 浙江工业大学 2025-03-04 CN disclosed
US-9278905-B2 Production method for compound comprising amino group and/or hydroxyl group KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-03-08 US disclosed
US-20150105559-A1 PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150105559-A1 PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP CA7, DAO, CA4 IDO1 510/4885PARP1 4712/4885TDP1 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.