SCHEMBL16640337

SCHEMBL16640337

OCCCOCC1CCCC1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.44
UGCG Q16739 2/20 0.44
GBA2 Q9HCG7 2/20 0.44
SPHK1 Q9NYA1 13/20 0.41
SPHK2 Q9NRA0 4/20 0.41
NAAA Q02083 1/20 0.36
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1164544 0.91 GBA1 (0.49) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL30225094 0.91 GBA1 (0.49) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL4603376 0.90
SCHEMBL1164989 0.89 GBA1 (0.51) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL31601986 0.86 GBA1 (0.44) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL20109731 0.86 MEN1 (0.39) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL7536089 0.86 GBA1 (0.44) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL21215385 0.84 MEN1 (0.50) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL13096717 0.83 TSHR (0.41) GBA1UGCGGBA2SPHK1SPHK2
SCHEMBL4592512 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572592-B2 Labelling compounds and their use in assays BINX HEALTH LIMITED (GB) 2023-02-07 US disclosed
US-20220025440-A1 LABELLING COMPOUNDS AND THEIR USE IN ASSAYS BINX HEALTH LIMITED (GB) 2022-01-27 US disclosed
US-10968490-B2 Labelling compounds and their use in assays BINX HEALTH LIMITED (GB) 2021-04-06 US disclosed
US-20180037937-A1 Labelling Compounds and Their Use in Assays KREOS CAPITAL VII (UK) LIMITED (GB) 2018-02-08 US disclosed
EP-3055317-B1 LABELLING COMPOUNDS AND THEIR USE IN ASSAYS ATLAS GENETICS LTD (GB) 2018-01-31 EP disclosed
US-9822398-B2 Labelling compounds and their use in assays ATLAS GENETICS LIMITED (GB) 2017-11-21 US disclosed
WO-2015052516-A1 LABELLING COMPOUNDS AND THEIR USE IN ASSAYS ATLAS GENETICS LIMITED (GB) 2015-04-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037937-A1 Labelling Compounds and Their Use in Assays CYP2F1, CYP4F3, CYP4F2 GBA1 366/4885UGCG 602/4885GBA2 733/4885
US-20220025440-A1 LABELLING COMPOUNDS AND THEIR USE IN ASSAYS CYP2F1, CYP4F3, CYP4F2 GBA1 366/4885UGCG 602/4885GBA2 733/4885
US-11572592-B2 Labelling compounds and their use in assays CYP2F1, CYP4F3, CYP4F2 GBA1 366/4885UGCG 602/4885GBA2 733/4885
US-10968490-B2 Labelling compounds and their use in assays CYP2F1, CYP4F3, CYP4F2 GBA1 366/4885UGCG 602/4885GBA2 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.