SCHEMBL16644297

SCHEMBL16644297

CC(=N)N1CCC(F)(F)C1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.38
DPP7 Q9UHL4 1/20 0.38
NAMPT P43490 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029490 0.77 DPP4 (0.45) DPP4DPP7NAMPT
Hydrochloric Acid SCHEMBL30806948 0.76 DPP4 (0.40) DPP4DPP7NAMPT
SCHEMBL15116593 0.74 DPP4 (0.42) DPP4DPP7NAMPT
SCHEMBL14655307 0.72 DPP4 (0.41) DPP4DPP7NAMPT
SCHEMBL15145140 0.70 DPP4 (0.37) DPP4DPP7NAMPT
SCHEMBL15701184 0.70 DPP4 (0.46) DPP4DPP7NAMPT
SCHEMBL4830838 0.70 DPP4 (0.46) DPP4DPP7NAMPT
SCHEMBL18191028 0.70 DPP4 (0.36) DPP4DPP7NAMPT
SCHEMBL2739927 0.70 DPP4 (0.54) DPP4DPP7NAMPT
SCHEMBL22163040 0.69 USP2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051713-A1 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRIDIN-2-ONE SPIRO DERIVATIVE, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 2015-04-16 WO disclosed