⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357148 | 0.80 | — | — | |
| SCHEMBL4755667 | 0.78 | — | — | |
| SCHEMBL18404146 | 0.78 | — | — | |
| SCHEMBL15677328 | 0.78 | — | — | |
| SCHEMBL24761048 | 0.73 | — | — | |
| SCHEMBL13896831 | 0.73 | — | — | |
| SCHEMBL18324400 | 0.73 | — | — | |
| SCHEMBL13177801 | 0.70 | — | — | |
| SCHEMBL18536346 | 0.70 | — | — | |
| SCHEMBL3132448 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017120355-A1 | DIHYDROQUINOLINES AND USES THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2017-07-13 | — | — | WO | disclosed |
| EP-2717916-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015054669-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC (US) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015054659-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |