Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 16/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 10/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635316 | 0.85 | PARP1 (0.63) | PARP1PARP2PARP3 | |
| SCHEMBL16645833 | 0.83 | PARP1 (0.60) | PARP1PARP2PARP3 | |
| SCHEMBL16645834 | 0.83 | PARP1 (0.60) | PARP1PARP2PARP3 | |
| SCHEMBL16645829 | 0.83 | PARP1 (0.60) | PARP1PARP2PARP3 | |
| SCHEMBL16645831 | 0.81 | PARP1 (0.61) | PARP1PARP2PARP3 | |
| SCHEMBL16635490 | 0.81 | PARP1 (0.61) | PARP1PARP2PARP3 | |
| SCHEMBL2265110 | 0.79 | PARP1 (0.71) | ALDH1A1PARP1MAPTKMT2APARP2 | |
| SCHEMBL2265978 | 0.79 | PARP1 (0.47) | PARP1PARP2PARP3 | |
| SCHEMBL16645828 | 0.79 | PARP1 (0.63) | PARP1PARP2PARP3 | |
| SCHEMBL1422526 | 0.79 | PARP1 (0.68) | ALDH1A1PARP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051766-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY (ADP-RIBOSE) POLYMERASE INHIBITORS | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-04-16 | — | — | WO | disclosed |