Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649300 | 0.97 | S1PR1 (0.68) | S1PR1FFAR1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL460309 | 0.90 | S1PR1 (0.79) | S1PR1S1PR5S1PR4 | |
| SCHEMBL16649254 | 0.89 | S1PR1 (0.83) | S1PR1FFAR1S1PR5S1PR4 | |
| SCHEMBL16648946 | 0.88 | S1PR1 (0.72) | S1PR1FFAR1S1PR5S1PR4 | |
| SCHEMBL16649289 | 0.87 | S1PR1 (0.84) | S1PR1FFAR1L3MBTL1S1PR5S1PR4 | |
| SCHEMBL460497 | 0.87 | S1PR1 (0.82) | S1PR1S1PR5S1PR4 | |
| SCHEMBL16649210 | 0.86 | S1PR1 (0.72) | S1PR1 | |
| SCHEMBL16649489 | 0.86 | S1PR1 (0.70) | S1PR1L3MBTL1 | |
| SCHEMBL16649406 | 0.85 | S1PR1 (0.85) | S1PR1 | |
| SCHEMBL16649339 | 0.85 | S1PR1 (0.74) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595969-B1 | Substituted 3-phenyl-1,2,4-oxadiazole compounds | BRISTOL MYERS SQUIBB CO (US) | 2015-04-22 | — | — | EP | claimed |