Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649328 | 0.91 | S1PR1 (0.60) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649148 | 0.91 | S1PR1 (0.81) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649318 | 0.90 | S1PR1 (0.68) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL460080 | 0.90 | S1PR1 (0.82) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL460081 | 0.90 | S1PR1 (0.82) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649290 | 0.89 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16648926 | 0.88 | S1PR1 (0.64) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649252 | 0.87 | S1PR1 (0.69) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649223 | 0.86 | S1PR1 (0.68) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16649388 | 0.85 | S1PR1 (0.82) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595969-B1 | Substituted 3-phenyl-1,2,4-oxadiazole compounds | BRISTOL MYERS SQUIBB CO (US) | 2015-04-22 | — | — | EP | claimed |