Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649448 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL16649761 | 0.86 | MAPK1 (0.39) | SLC6A2SLC6A3SLC6A4KDM1AKCNH2 | |
| SCHEMBL12498977 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4KDM1AKCNH2 | |
| SCHEMBL16690824 | 0.86 | MAPK1 (0.39) | SLC6A2SLC6A3SLC6A4KDM1AKCNH2 | |
| SCHEMBL16649529 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4KDM1AKCNH2 | |
| SCHEMBL16649573 | 0.83 | KDM1A (0.66) | KDM1AKCNH2KDM1B | |
| SCHEMBL16649683 | 0.83 | KDM1A (0.52) | SLC6A2SLC6A3SLC6A4KDM1A | |
| SCHEMBL16649666 | 0.83 | KDM1A (0.66) | KDM1AKCNH2KDM1B | |
| SCHEMBL16133827 | 0.81 | KDM1A (0.57) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL16109604 | 0.81 | KDM1A (0.57) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |