SCHEMBL1665169

SCHEMBL1665169

CC(C)(C)[Si](C)(C)OC1CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20721984 0.86 PPM1D (0.31)
SCHEMBL3868726 0.86
SCHEMBL3860225 0.84 PPM1D (0.30)
SCHEMBL3860508 0.82
SCHEMBL3860507 0.82
SCHEMBL3868184 0.81
SCHEMBL3864820 0.81
SCHEMBL3868187 0.81
SCHEMBL5974530 0.81
SCHEMBL3870040 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483300-A4 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INST OF TECHN (US) 2009-04-08 EP claimed
US-7034096-B2 Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-25 US claimed
US-6987154-B2 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-01-17 US claimed
EP-1483300-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2004-12-08 EP claimed
US-20030236377-A1 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-12-25 US claimed
US-20030236367-A1 Ring-expansion of cyclic olefins by olefin metathesis reactions with an acyclic diene CALIFORNIA INSTITUE OF TECHNOLOGY 2003-12-25 US claimed
WO-2003070779-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-08-28 WO claimed
EP-4743447-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
EP-4743178-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
US-12435057-B2 Triazole carboxylic acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2025-10-07 US disclosed
US-12384768-B2 Isoxazole carboxylic acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-12 US disclosed
CN-119613408-A Bicyclic ketone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2025-03-14 CN disclosed
WO-2025016909-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
EP-1483300-A4 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INST OF TECHN (US) 2009-04-08 EP disclosed
US-7034096-B2 Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-25 US disclosed
US-6987154-B2 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-01-17 US disclosed
EP-1483300-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2004-12-08 EP disclosed
US-20030236367-A1 Ring-expansion of cyclic olefins by olefin metathesis reactions with an acyclic diene CALIFORNIA INSTITUE OF TECHNOLOGY 2003-12-25 US disclosed
US-20030236377-A1 Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-12-25 US disclosed
WO-2003070779-A1 RING EXPANSION OF CYCLIC-OLEFINS BY OLEFIN METATHESIS REACTIONS WITH AN ACYCLIC DIENE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-08-28 WO disclosed