Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836036 | 1.00 | CYP1A2 (0.42) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL27770958 | 0.90 | CYP1A2 (0.41) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL888064 | 0.87 | CYP1A2 (0.44) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL4428319 | 0.82 | CYP1A2 (0.39) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL30291130 | 0.80 | CYP1A2 (0.65) | CYP1A2TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL888140 | 0.80 | CYP1A2 (0.40) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL28135355 | 0.80 | SNCA (0.47) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL679338 | 0.80 | CYP1A2 (0.65) | CYP1A2TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL14676339 | 0.80 | CYP1A2 (0.40) | CYP1A2SNCATSHRPDK1ALDH1A1 | |
| SCHEMBL11077316 | 0.79 | CYP1A2 (0.69) | CYP1A2SNCAPDK1ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010646-B | Photoinduction synthesis method of indolone compound | 南京大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-115010646-A | Photoinduction synthesis method of indolone compounds | 南京大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-103588839-A | Nucleotides and nucleosides and method for their use in DNA sequencing | LASERGEN INC | 2014-02-19 | — | — | CN | disclosed |
| CN-102264917-A | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| EP-2125856-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008070749-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2008-06-12 | — | — | WO | disclosed |