Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.60 |
| ▸ | EP300 | Q09472 | 2/20 | 0.59 |
| ▸ | BRD2 | P25440 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | TSPO | P30536 | 1/20 | 0.56 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.56 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654653 | 0.91 | BRD4 (0.63) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654832 | 0.88 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654565 | 0.88 | BRD4 (0.61) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654821 | 0.87 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654963 | 0.87 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654792 | 0.87 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654729 | 0.87 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654767 | 0.86 | BRD4 (0.63) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654689 | 0.86 | BRD4 (0.58) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16654548 | 0.86 | BRD4 (0.58) | BRD4EP300BRD2ADORA2BTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057586-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058160-A1 | BROMODOMAIN INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2015-04-23 | — | — | WO | claimed |