Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654965 | 0.92 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16654363 | 0.91 | BRD4 (0.58) | BRD4 | |
| SCHEMBL16654866 | 0.88 | BRD4 (0.53) | BRD4 | |
| SCHEMBL16654754 | 0.85 | BRD4 (0.69) | BRD4 | |
| SCHEMBL29849059 | 0.84 | BRD4 (0.75) | BRD4 | |
| SCHEMBL16651312 | 0.84 | BRD4 (0.75) | BRD4 | |
| SCHEMBL16654853 | 0.83 | BRD4 (0.70) | BRD4 | |
| SCHEMBL16658118 | 0.83 | BRD4 (0.75) | BRD4 | |
| SCHEMBL16715340 | 0.82 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16655112 | 0.82 | BRD4 (0.50) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057586-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015058160-A1 | BROMODOMAIN INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2015-04-23 | — | — | WO | disclosed |