Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127387 | 0.94 | GLA (0.44) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL29742941 | 0.93 | GLA (0.46) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL246863 | 0.93 | GLA (0.44) | GLAPER2CRY1CRY2POLB | |
| Water SCHEMBL22611645 | 0.91 | GLA (0.43) | GLAPER2CRY1CRY2POLB | |
| Water SCHEMBL29402591 | 0.91 | GLA (0.46) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL3255714 | 0.90 | GLA (0.42) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL246864 | 0.81 | GLA (0.43) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL29394587 | 0.81 | GLA (0.43) | GLAPER2CRY1CRY2POLB | |
| SCHEMBL242608 | 0.81 | MEN1 (0.33) | GLAPER2CRY1CRY2CYP2C19 | |
| Water SCHEMBL30327713 | 0.81 | GLA (0.42) | GLAPER2CRY1CRY2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306201-B1 | Methods and compositions for assaying homocysteine | GEN ATOMICS (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-1644741-B1 | METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE | GEN ATOMICS (US) | 2011-08-31 | — | — | EP | disclosed |
| EP-2306201-A1 | Methods and compositions for assaying homocysteine | GENERAL ATOMICS (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2235201-A1 | METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE | GENERAL ATOMICS (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009089106-A1 | METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE | GENERAL ATOMICS (US) | 2009-07-16 | — | — | WO | disclosed |
| US-7097968-B2 | Methods and compositions for assaying homocysteine | GENERAL ATOMICS (US) | 2006-08-29 | — | — | US | disclosed |
| US-20050009128-A1 | Methods and compositions for assaying homocysteine | DIAZYME LABORATORIES, INC. | 2005-01-13 | — | — | US | disclosed |