Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 14/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634098 | 1.00 | TLR8 (0.44) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16634100 | 1.00 | TLR8 (0.44) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16633743 | 0.92 | TLR8 (0.46) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16633745 | 0.92 | TLR8 (0.46) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16632384 | 0.91 | TLR8 (0.46) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16632382 | 0.91 | TLR8 (0.46) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16634185 | 0.89 | TLR8 (0.44) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16634188 | 0.89 | TLR8 (0.44) | TLR8TLR9TLR7KDM4EALDH1A1 | |
| SCHEMBL16633912 | 0.89 | TLR8 (0.45) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16633914 | 0.89 | TLR8 (0.45) | TLR8TLR9TLR7ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057964-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2016-08-24 | — | — | EP | claimed |
| WO-2015057659-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | claimed |