SCHEMBL16655449

SCHEMBL16655449

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/COP(=O)(OC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)OP(=O)(OC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)OC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 14/20 0.69
FNTB P49356 12/20 0.69
PGGT1B P53609 5/20 0.69
ALDH1A1 P00352 1/20 0.54
ALOX15 P16050 1/20 0.54
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18042460 1.00 FNTA (0.69) FNTAFNTBPGGT1BALDH1A1ALOX15
SCHEMBL1978483 1.00 FNTA (0.69) FNTAFNTBPGGT1BALDH1A1ALOX15
SCHEMBL109366 0.98 FNTA (0.67) FNTAFNTBPGGT1BALDH1A1ALOX15
SCHEMBL18042466 0.93 FNTA (0.69) FNTAFNTBPGGT1BALDH1A1ALOX15
SCHEMBL3884435 0.92 FNTA (0.78) FNTAFNTBPGGT1B
Pyrophosphoric Acid SCHEMBL16987380 0.92 FNTA (0.73) FNTAFNTBPGGT1B
SCHEMBL34468137 0.92 FNTA (0.78) FNTAFNTBPGGT1B
SCHEMBL28408955 0.92 FNTA (0.78) FNTAFNTBPGGT1B
SCHEMBL1759376 0.92 FNTA (0.78) FNTAFNTBPGGT1B
SCHEMBL30009312 0.92 FNTA (0.78) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3057975-A1 N-GLYCOSYLATION OF PEPTIDES AND PROTEINS Oxford University Innovation Limited (GB) 2016-08-24 EP disclosed
WO-2015056011-A1 N-GLYCOSYLATION OF PEPTIDES AND PROTEINS ISIS INNOVATION LIMITED (GB) 2015-04-23 WO disclosed