Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.66 |
| ▸ | BTK | Q06187 | 12/20 | 0.66 |
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | HCK | P08631 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655649 | 1.00 | PIK3CD (0.66) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655748 | 0.94 | PIK3CD (0.63) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655751 | 0.94 | PIK3CD (0.63) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655706 | 0.90 | PIK3CD (0.70) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655635 | 0.89 | PIK3CD (0.65) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655639 | 0.89 | PIK3CD (0.65) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655974 | 0.88 | PIK3CD (0.67) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL23917465 | 0.87 | PIK3CD (0.73) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655773 | 0.87 | PIK3CD (0.70) | PIK3CDBTKEGFRPIK3CGABL1 | |
| SCHEMBL16655733 | 0.85 | PIK3CD (0.70) | PIK3CDBTKEGFRPIK3CGABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |