Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.62 |
| ▸ | ATR | Q13535 | 4/20 | 0.62 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | ITK | Q08881 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655939 | 0.89 | PIK3CD (0.69) | BTKPIK3CDATREGFRLYN | |
| SCHEMBL23908597 | 0.86 | BTK (0.61) | BTKPIK3CDATREGFRLYN | |
| SCHEMBL16665687 | 0.85 | PIK3CD (0.75) | BTKPIK3CDATREGFR | |
| SCHEMBL16656048 | 0.85 | PIK3CD (0.75) | BTKPIK3CDATREGFR | |
| SCHEMBL16665679 | 0.83 | PIK3CD (0.73) | BTKPIK3CDATREGFR | |
| SCHEMBL16655397 | 0.83 | PIK3CD (0.73) | BTKPIK3CDATREGFR | |
| SCHEMBL16655386 | 0.83 | PIK3CD (0.77) | BTKPIK3CDATREGFRLYN | |
| SCHEMBL16655577 | 0.83 | BTK (0.67) | BTKPIK3CDATREGFRITK | |
| SCHEMBL16655275 | 0.83 | ATR (0.72) | BTKPIK3CDATREGFRITK | |
| SCHEMBL16655402 | 0.83 | PIK3CD (0.90) | BTKPIK3CDATREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | claimed |
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | BTK 1/4885PIK3CD 2/4885ATR 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.