SCHEMBL1665612

SCHEMBL1665612

COC(OC)N1CCNC1=O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TOP2A P11388 1/20 0.32
TOP2B Q02880 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28173246 0.81 TOP2A (0.34) ALOX5HSD17B10TOP2ATOP2BNPSR1
SCHEMBL992853 0.75
SCHEMBL16178016 0.72 ADORA2A (0.33) HSD17B10TOP2ATOP2BALDH1A1
SCHEMBL16061311 0.72 ADORA2A (0.33) HSD17B10TOP2ATOP2BALDH1A1
SCHEMBL16059003 0.72 ADORA2A (0.33) HSD17B10TOP2ATOP2BALDH1A1
SCHEMBL16915160 0.71 RET (0.38) ALOX5ALDH1A1KDM4EPOLB
SCHEMBL367449 0.71
SCHEMBL7552234 0.71
SCHEMBL21217110 0.71
SCHEMBL29237864 0.71 TOP2A (0.36) TOP2ATOP2BNPSR1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2228400-B1 NOVEL POLYIMIDE SILICONE, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE NOVEL POLYIMIDE SILICONE, AND METHOD FOR PATTERN FORMATION SHINETSU CHEMICAL CO (JP) 2016-04-27 EP disclosed
US-8263308-B2 Polyimide silicone, photosensitive resin composition containing the novel polyimide silicone, and method for pattern formation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-09-11 US disclosed
US-8048611-B2 Polyorganosiloxane, resin composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-01 US disclosed
EP-2112188-B1 Polyorganosiloxane, resin composition, and patterning process SHINETSU CHEMICAL CO (JP) 2011-04-27 EP disclosed
US-20100233619-A1 NOVEL POLYIMIDE SILICONE, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE NOVEL POLYIMIDE SILICONE, AND METHOD FOR PATTERN FORMATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-16 US disclosed
EP-2228400-A1 Novel polyimide silicone, photosensitive resin composition containing the novel polyimide silicone, and method for pattern formation Shin-Etsu Chemical Co., Ltd. (JP) 2010-09-15 EP disclosed
US-20090269697-A1 POLYORGANOSILOXANE, RESIN COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-10-29 US disclosed
EP-2112188-A1 Polyorganosiloxane, resin composition, and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2009-10-28 EP disclosed
US-7030007-B2 Via-filling material and process for fabricating semiconductor integrated circuit using the material MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2006-04-18 US disclosed
US-20050101123-A1 Via-filling material and process for fabricating semiconductor integrated circuit using the material MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2005-05-12 US disclosed
US-6287746-B1 PHOTOACID GENERATOR NEC CORPORATION (JP) 2001-09-11 US disclosed
US-6030747-A CHEMICALLY AMPLIFIED RESIST CONSISTS OF A PHOTOACID GENERATOR, A CROSSLINKING AGENT ACTIVATED IN PRESENCE OF ACID AND A COPOLYMER OF ACRYLIC OR METHACRYLIC ESTER CONTAINING AN ACID, HYDROXY OR ESTER POLAR GROUP AND A COMPOUND NEC CORPORATION (JP) 2000-02-29 US disclosed
US-4341650-A Chemically stabilized azulmic acids, processes for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1982-07-27 US disclosed
US-4283219-A PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-11 US disclosed
US-4263181-A Chemically stabilized azulmic acids, processes for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
US-4052158-A CATALYTIC FREE RADICAL POLYMERIZATION, CURING STAUFFER CHEMICAL COMPANY (US) 1977-10-04 US disclosed