Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 14/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018609 | 1.00 | SLC5A2 (0.40) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018604 | 0.92 | CHRNA7 (0.36) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018640 | 0.91 | CHRNA7 (0.35) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018651 | 0.90 | SLC5A2 (0.37) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018612 | 0.90 | SLC5A2 (0.36) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018673 | 0.89 | SLC5A2 (0.41) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018603 | 0.89 | SLC5A2 (0.41) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018646 | 0.89 | CHRNA7 (0.36) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018688 | 0.88 | CHRNA7 (0.36) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 | |
| SCHEMBL16018669 | 0.88 | CHRNA7 (0.33) | SLC5A2SLC5A1CHRNA7SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012412-B2 | Dual SGLT1/SGLT2 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-21 | — | — | US | disclosed |