Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657393 | 0.88 | GRM5 (0.71) | GRM5CHRNA4 | |
| SCHEMBL1657952 | 0.88 | GRM5 (0.71) | GRM5CHRNA4 | |
| SCHEMBL1658764 | 0.87 | GRM5 (0.66) | GRM5CHRNA4 | |
| SCHEMBL1657740 | 0.87 | GRM5 (0.66) | GRM5CHRNA4 | |
| SCHEMBL1658048 | 0.87 | GRM5 (0.66) | GRM5CHRNA4 | |
| SCHEMBL1659776 | 0.87 | GRM5 (0.72) | GRM5 | |
| SCHEMBL1657241 | 0.83 | GRM5 (0.66) | GRM5 | |
| SCHEMBL1657722 | 0.82 | GRM5 (0.59) | GRM5 | |
| SCHEMBL1658399 | 0.82 | GRM5 (0.75) | GRM5 | |
| SCHEMBL1657521 | 0.82 | GRM5 (0.97) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490541-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2012-08-29 | — | — | EP | claimed |
| WO-2011050063-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-04-28 | — | — | WO | claimed |