SCHEMBL16657271

SCHEMBL16657271

CC(C)(N)Sc1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
APOBEC3G Q9HC16 1/20 0.52
CYP3A4 P08684 4/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
ALOX15 P16050 2/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TSHR P16473 2/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6863388 0.84 KMT2A (0.54) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL19557713 0.80 MEN1 (0.50) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL11093928 0.77 MAPT (0.46) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL2197151 0.74 MAPT (0.54) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL29549836 0.74 MAPT (0.54) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL398169 0.74 MAPT (0.54) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL11356253 0.74 MEN1 (0.50) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL19900554 0.71 MEN1 (0.62) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL7006953 0.71 MAPT (0.50) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL19557730 0.71 MEN1 (0.50) MEN1KMT2AMAPTNPSR1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015057561-A1 METHOD OF IMPROVING THE MELT PROPERTIES OF POLY(ARYLENE SULFIDE) POLYMERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-23 WO disclosed