Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 13/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634343 | 1.00 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL24404851 | 1.00 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16633712 | 1.00 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16634345 | 1.00 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL19829013 | 1.00 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| Hydrochloric Acid SCHEMBL16633213 | 0.99 | TLR8 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16633862 | 0.99 | TLR9 (0.49) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16633859 | 0.99 | TLR9 (0.49) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16634196 | 0.96 | TLR9 (0.48) | TLR8TLR9TLR7KDM4ERAD52 | |
| SCHEMBL16634200 | 0.96 | TLR9 (0.48) | TLR8TLR9TLR7KDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057659-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |