Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 16/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633981 | 1.00 | TLR8 (0.53) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL20626592 | 1.00 | TLR8 (0.53) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL25701692 | 0.91 | TLR8 (0.52) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16633326 | 0.90 | TLR8 (0.53) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16633347 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16634353 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL19828894 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16634116 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16633924 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA | |
| SCHEMBL16634109 | 0.90 | TLR8 (0.51) | TLR8TLR9TLR7ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995495-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2022-05-11 | — | — | EP | disclosed |
| WO-2015057659-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |