Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666314 | 0.90 | CCR1 (0.45) | CCR1NR1I2 | |
| SCHEMBL1665453 | 0.88 | CCR1 (0.49) | CCR1NR1I2 | |
| SCHEMBL1665900 | 0.86 | CCR1 (0.50) | CCR1NR1I2 | |
| SCHEMBL3943502 | 0.83 | CCR1 (0.60) | CCR1NR1I2 | |
| SCHEMBL1665459 | 0.83 | CCR1 (0.55) | CCR1NR1I2 | |
| SCHEMBL11903642 | 0.83 | CCR1 (0.56) | CCR1NR1I2 | |
| SCHEMBL11903631 | 0.83 | CCR1 (0.56) | CCR1NR1I2 | |
| SCHEMBL17599561 | 0.83 | CCR1 (0.56) | CCR1NR1I2 | |
| SCHEMBL1665894 | 0.82 | CCR1 (0.54) | CCR1NR1I2 | |
| SCHEMBL17599565 | 0.82 | CCR1 (0.55) | CCR1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486034-A1 | SPIROCYCLIC COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044197-A1 | SPIROCYCLIC COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-14 | — | — | WO | disclosed |