Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079723 | 0.88 | BTK (0.42) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL15079677 | 0.88 | BTK (0.42) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL2709814 | 0.87 | BTK (0.44) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL2709810 | 0.87 | BTK (0.44) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL31084800 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL31084801 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL31084799 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL15078163 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL31084797 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA | |
| SCHEMBL31084798 | 0.86 | BTK (0.46) | BTKKDM1AGAAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407450-B1 | Method for producing optically active diamine derivative | DAIICHI SANKYO CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |