Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25263347 | 0.76 | PARP1 (0.30) | PARP1 | |
| SCHEMBL30259052 | 0.76 | PARP1 (0.30) | PARP1 | |
| SCHEMBL14451069 | 0.76 | CCR1 (0.34) | PARP1 | |
| SCHEMBL25064264 | 0.76 | MAPK13 (0.30) | PARP1 | |
| SCHEMBL30364177 | 0.76 | MAPK13 (0.30) | PARP1 | |
| SCHEMBL12395081 | 0.73 | ATM (0.34) | — | |
| SCHEMBL30525181 | 0.71 | PARP1 (0.56) | PARP1 | |
| SCHEMBL22838646 | 0.69 | HTR2A (0.33) | — | |
| SCHEMBL25223217 | 0.66 | — | — | |
| SCHEMBL30258819 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058031-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-04-23 | — | — | WO | disclosed |