Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.83 |
| ▸ | FGFR4 | P22455 | 10/20 | 0.83 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.79 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16659399 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL17728860 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL17728856 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16659481 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16659434 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16659594 | 0.91 | FGFR4 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16659606 | 0.88 | FGFR2 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL17728840 | 0.88 | FGFR4 (0.82) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL17728842 | 0.88 | FGFR4 (0.82) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL17728841 | 0.88 | FGFR4 (0.82) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |