Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654403 | 0.89 | FGFR4 (0.41) | FGFR4FGFR1 | |
| SCHEMBL16659627 | 0.89 | FGFR3 (0.33) | FGFR4FGFR1 | |
| SCHEMBL16654119 | 0.77 | FGFR3 (0.35) | FGFR4FGFR1 | |
| SCHEMBL16655847 | 0.76 | FGFR4 (0.42) | FGFR4FGFR1 | |
| SCHEMBL16655438 | 0.76 | FGFR1 (0.44) | FGFR4FGFR1 | |
| SCHEMBL16655790 | 0.74 | FGFR1 (0.44) | FGFR1 | |
| SCHEMBL28767434 | 0.74 | FGFR1 (0.33) | FGFR4FGFR1 | |
| SCHEMBL28767438 | 0.73 | FGFR3 (0.42) | FGFR4FGFR1 | |
| SCHEMBL22157649 | 0.72 | FGFR4 (0.32) | FGFR4FGFR1 | |
| SCHEMBL16665253 | 0.71 | FGFR1 (0.33) | FGFR4FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |