Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 15/20 | 0.36 |
| ▸ | EGFR | P00533 | 15/20 | 0.36 |
| ▸ | HCK | P08631 | 15/20 | 0.36 |
| ▸ | SRC | P12931 | 15/20 | 0.36 |
| ▸ | KDR | P35968 | 15/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.36 |
| ▸ | MTOR | P42345 | 15/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.36 |
| ▸ | PRKDC | P78527 | 15/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 14/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 11/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665708 | 0.90 | PIK3CD (0.41) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16655408 | 0.77 | PIK3CD (0.67) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16665722 | 0.69 | SRC (0.34) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16655470 | 0.69 | PIK3CD (0.66) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16665849 | 0.68 | PIK3CD (0.53) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16655320 | 0.67 | PIK3CD (0.61) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16655964 | 0.67 | PIK3CD (0.61) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16665745 | 0.67 | PIK3CD (0.51) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16655584 | 0.64 | PIK3CD (0.52) | PIK3CDBTKABL1EGFRHCK | |
| SCHEMBL16665776 | 0.64 | BTK (0.40) | PIK3CDBTKABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |