Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.36 |
| ▸ | PRKDC | P78527 | 7/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665750 | 0.86 | FGFR1 (0.39) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16665742 | 0.80 | PIK3CG (0.41) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917472 | 0.77 | SRC (0.52) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16065725 | 0.75 | PIK3CD (0.53) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16665792 | 0.74 | SRC (0.45) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19414400 | 0.72 | CYP1A1 (0.47) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL11405 | 0.71 | PIK3CG (0.61) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917564 | 0.71 | FGFR1 (0.43) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16655314 | 0.70 | PIK3CD (0.69) | SRCABL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL11325 | 0.70 | PIK3CG (0.49) | SRCABL1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |