Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896535 | 1.00 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL22845449 | 1.00 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2788911 | 1.00 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7736125 | 0.88 | MAPT (0.56) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12424055 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2198082 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL13473785 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2200914 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2197855 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1417633 | 0.86 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250185-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-09-01 | — | — | US | disclosed |
| WO-2015060702-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2015-04-30 | — | — | WO | disclosed |