⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397012 | 1.00 | — | — | |
| SCHEMBL147942 | 1.00 | — | — | |
| SCHEMBL1112528 | 1.00 | — | — | |
| SCHEMBL1112532 | 1.00 | — | — | |
| SCHEMBL147941 | 1.00 | — | — | |
| SCHEMBL3986701 | 1.00 | — | — | |
| SCHEMBL1397014 | 1.00 | — | — | |
| SCHEMBL1541739 | 1.00 | — | — | |
| SCHEMBL1541066 | 0.96 | — | — | |
| SCHEMBL1113741 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207268-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-06-27 | — | — | US | claimed |
| EP-4313053-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2024-02-07 | — | — | EP | claimed |
| CN-114539078-B | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114539078-A | Active small molecular probe for specifically sorting monoamine oxidase, preparation method and application thereof | 南京工业大学 | 2022-05-27 | — | — | CN | claimed |
| US-20190337939-A1 | NANOLUC SUICIDE SUBSTRATES | PROMEGA CORPORATION | 2019-11-07 | — | — | US | claimed |
| US-20240207268-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-06-27 | — | — | US | disclosed |
| US-20240191211-A1 | BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING | PROMEGA CORPORATION | 2024-06-13 | — | — | US | disclosed |
| US-20240165259-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| US-20240059784-A1 | TRANSFERRIN RECEPTOR BINDING PROTEINS AND CONJUGATES | ELI LILLY AND COMPANY | 2024-02-22 | — | — | US | disclosed |
| EP-4320073-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-4313053-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2024-02-07 | — | — | EP | disclosed |
| CN-117337267-A | Bioorthogonal reactions suitable for click/click cancellation applications | 达纳－法伯癌症研究所公司 | 2024-01-02 | — | — | CN | disclosed |
| US-10274490-B2 | Magnetic labeling of bacteria | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-30 | — | — | US | disclosed |
| US-10087199-B2 | Super-resolution imaging compositions and methods using same | YALE UNIVERSITY (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3357903-A1 | METHOD AND SYSTEM FOR A CONTINUOUS PRODUCTION OF A Z-CYCLOOCTENE | Stichting Katholieke Universiteit (NL) | 2018-08-08 | — | — | EP | disclosed |
| WO-2018045245-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2018-03-08 | — | — | WO | disclosed |
| WO-2017212329-A1 | CLIPTAC COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-12-14 | — | — | WO | disclosed |
| US-20160223559-A1 | TETRAZINE-CONTAINING COMPOUNDS AND SYNTHETIC METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-08-04 | — | — | US | disclosed |
| US-20160115180-A1 | Novel Super-Resolution Imaging Compositions and Methods Using Same | YALE UNIVERSITY | 2016-04-28 | — | — | US | disclosed |
| US-20150125884-A1 | Magnetic Labeling of Bacteria | THE GENERAL HOSPITAL CORPORATION | 2015-05-07 | — | — | US | disclosed |