SCHEMBL16682387

SCHEMBL16682387

CC1C(OC(=O)c2ccccc2)C(O)OC(COC(=O)c2ccccc2)C1OC1OC(COC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 4/20 0.48
▸ ANTXR2 P58335 3/20 0.47
▸ USP2 O75604 2/20 0.47
▸ F11 P03951 2/20 0.47
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ TMPRSS2 O15393 1/20 0.47
▸ PDE5A O76074 1/20 0.47
▸ HMGCR P04035 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ LCK P06239 1/20 0.47
▸ FYN P06241 1/20 0.47
▸ HSPD1 P10809 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CA6 P23280 1/20 0.47
▸ TBXAS1 P24557 1/20 0.47
▸ MAPK3 P27361 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ HSPE1 P61604 1/20 0.47
▸ MAPK14 Q16539 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3701684 0.92 PTPN1 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL16384144 0.92 ANTXR2 (0.49) PTPN1ANTXR2USP2F11CA1
SCHEMBL12119535 0.91 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL13030058 0.91 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL12997557 0.91 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL806359 0.91 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL12122526 0.91 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1
SCHEMBL23266721 0.89 PTPN1 (0.50) PTPN1ANTXR2USP2F11CA1
SCHEMBL16299275 0.88 PTPN1 (0.47) PTPN1ANTXR2USP2F11CA1
SCHEMBL17849747 0.87 ANTXR2 (0.53) PTPN1ANTXR2USP2F11CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9352048-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2016-05-31 — — US disclosed
US-20150119445-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides BANK OF AMERICA, N.A. 2015-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119445-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides LPXN, ZYX, OSTC PTPN1 1472/4885ANTXR2 2132/4885USP2 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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