SCHEMBL1668282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL1668379	0.99	CRACR2A (0.75)	CRACR2AORAI1SMN1; SMN2NPC1MAPT
	SCHEMBL1667966	0.88	CRACR2A (0.81)	CRACR2AORAI1
	SCHEMBL1668296	0.87	CRACR2A (1.00)	CRACR2AORAI1GAA
	SCHEMBL1668343	0.87	CRACR2A (0.76)	CRACR2AORAI1EPHX2
	SCHEMBL1668068	0.86	CRACR2A (0.78)	CRACR2AORAI1EPHX2
	Hydrochloric Acid SCHEMBL1669024	0.86	CRACR2A (0.75)	CRACR2AORAI1EPHX2
	SCHEMBL1668102	0.86	EPHX2 (0.74)	CRACR2AORAI1SMN1; SMN2NPC1MAPT
	Hydrochloric Acid SCHEMBL1667869	0.86	CRACR2A (0.98)	CRACR2AORAI1GAA
	SCHEMBL1668383	0.85	CRACR2A (0.79)	CRACR2AORAI1
	Hydrochloric Acid SCHEMBL1883215	0.84	CRACR2A (0.77)	CRACR2AORAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.