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SCHEMBL16684725

SCHEMBL16684725

Cc1cc(I)cc(C)c1-c1cccc(COc2ccc3c(c2)OCC3CC(=O)O)c1

nearest known ligand 0.86

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 20/20 0.86
▸ GNA15 P30679 1/20 0.73
▸ SLC10A1 Q14973 1/20 0.73
▸ ABCC2 Q92887 1/20 0.73
▸ SLCO1B3 Q9NPD5 1/20 0.73
▸ SLCO1B1 Q9Y6L6 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450662 0.93 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL15125767 0.93 FFAR1 (0.89) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL16249163 0.93 FFAR1 (0.89) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL1632685 0.93 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL1633142 0.92 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL16684804 0.91 FFAR1 (0.72) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL16690557 0.89 FFAR1 (0.91) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL15125882 0.87 FFAR1 (0.85) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL15125719 0.87 FFAR1 (0.85) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL15125897 0.87 FFAR1 (0.79) FFAR1GNA15SLC10A1ABCC2SLCO1B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015062486-A1 BIPHENYL COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2015-05-07 — — WO disclosed