⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814784 | 0.71 | — | — | |
| SCHEMBL92519 | 0.63 | — | — | |
| SCHEMBL13217143 | 0.63 | — | — | |
| SCHEMBL1928370 | 0.62 | — | — | |
| SCHEMBL19347197 | 0.62 | — | — | |
| SCHEMBL22761418 | 0.60 | — | — | |
| SCHEMBL19429460 | 0.60 | TSHR (0.43) | — | |
| SCHEMBL4621674 | 0.59 | — | — | |
| SCHEMBL14941633 | 0.59 | — | — | |
| SCHEMBL15564067 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233849-A1 | HETEROARYLALKYLENE ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. Hoffmann-La Roche AG (CH) | 2017-10-25 | — | — | EP | claimed |
| WO-2016096936-A1 | HETEROARYLALKYLENE ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2016-06-23 | — | — | WO | claimed |
| EP-0734381-B1 | MORPHOLINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-07-05 | — | — | EP | claimed |
| US-12110279-B2 | Triazolones, tetrazolones, and imidazolones, or their salts, and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2024-10-08 | — | — | US | disclosed |
| EP-4326715-A1 | TRIAZOLONES, TETRAZOLONES, AND IMIDAZOLONES, OR THEIR SALTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2024-02-28 | — | — | EP | disclosed |
| CN-117203205-A | Triazolone, tetrazolone and imidazolone or salts thereof, and pharmaceutical compositions containing the same | 柳韩洋行 | 2023-12-08 | — | — | CN | disclosed |
| US-20230340018-A1 | MPRO CYSTEINE PROTEASE INHIBITORS | ANIXA BIOSCIENCES, INC. | 2023-10-26 | — | — | US | disclosed |
| WO-2023205424-A2 | LIPID COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY | GREENLIGHT BIOSCIENCES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-3483143-B1 | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2023-10-18 | — | — | EP | disclosed |
| US-11786608-B2 | Isoquinolinyl triazolone complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | disclosed |
| EP-3377474-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |
| US-5965742-A | Selective chlorination of a 1-(2-fluorophenyl)-1,2,4-triazole | FMC CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5965742-A | Selective chlorination of a 1-(2-fluorophenyl)-1,2,4-triazole | FMC CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0889882-A1 | SELECTIVE CHLORINATION OF A 1-(2-FLUOROPHENYL)-1,2,4-TRIAZOLE | FMC CORPORATION (US) | 1999-01-13 | — | — | EP | disclosed |
| EP-0889882-A1 | SELECTIVE CHLORINATION OF A 1-(2-FLUOROPHENYL)-1,2,4-TRIAZOLE | FMC CORPORATION (US) | 1999-01-13 | — | — | EP | disclosed |
| CN-1203591-A | Selective chlorination of 1-(2-fluorophenyl)-1,2,4-triazole | FMC CORP (US) | 1998-12-30 | — | — | CN | disclosed |
| CN-1203591-A | Selective chlorination of 1-(2-fluorophenyl)-1,2,4-triazole | FMC CORP (US) | 1998-12-30 | — | — | CN | disclosed |
| WO-1997024337-A1 | SELECTIVE CHLORINATION OF A 1-(2-FLUOROPHENYL)-1,2,4-TRIAZOLE | FMC CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024337-A1 | SELECTIVE CHLORINATION OF A 1-(2-FLUOROPHENYL)-1,2,4-TRIAZOLE | FMC CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5468868-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one | FMC CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |